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My top 20 nonfiction picks

For nearly three-and-a-half years now, I’ve been posting book reviews in this blog, typically twice a week. For my own benefit as well as yours, I like to look back every so often at the books I’ve read and think about what I’ve learned from them. What follows below is a list of the 20 nonfiction books (out of more than 100 I read) that have added the most to my understanding of the world. They’re arranged in no particular order: I can’t imagine trying to pick the best of this lot!

Going Clear: Scientology, Hollywood, and the Prison of Belief, by Lawrence Wright

The definitive study of the belief system known as Scientology, with an emphasis on its human rights violations and the Hollywood celebrities it has gathered into its “prison of belief.”

Mary’s Mosaic: The CIA Conspiracy to Murder John F. Kennedy, Mary Pinchot Meyer, and Their Vision for World Peace, by Peter Janney

Revelations galore from newly unearthed evidence about the assassination of John F. Kennedy and his last years in the White House.

The Swerve: How the World Became Modern, by Stephen Greenblatt

The seminal role of a long-forgotten  ancient Greek poet and philosopher on the thinking of the geniuses who shaped the Renaissance and on the course of history that followed.

The Revenge of Geography: What the Map Tells Us About Coming Conflicts and the Battle Against Fate, by Robert D. Kaplan

Recent history and current events through the distorting lens of geopolitics, which views Planet Earth, and the machinations and foibles of earthly leaders, from a very different perspective than is found in most history books.

Freedom’s Forge: How American Business Produced Victory in World War II, by Arthur Herman

The astonishing story of America’s rearmament in World War II, with a focus on the two larger-than-life personalities who made it happen through sheer force of will: William Knudsen and Henry J. Kaiser.

Double Cross: The True Story of the D-Day Spies, by Ben McIntyre

The stranger-than-fiction story of the British double agents whose brilliant work in Europe played a pivotal role in the success of the Normandy Invasion.

The Power of Unreasonable People: How Social Entrepreneurs Create Markets That Change the World, by John Elkington and Pamela Hartigan

A comprehensive and well-informed view of the world of social enterprise and the extraordinary individuals who stand out in a field that attracts brilliant and inspired people by the carload.

The Self-Made Myth, and the Truth About How Government Helps Individuals and Businesses Succeed, by Brian Miller and Mike Lapham

An in-depth refutation of the myth of rugged individualism, lionized by Ayn Rand’s novels and enshrined in conservative and libertarian ideology for four decades.

The New Jim Crow: Mass Incarceration in the Age of Colorblindness, by Michelle Alexander

How the War on Drugs, and the institutionalized racism that undergirds it, has weakened American society and fostered a new underclass dominated by young men of color.

Behind the Beautiful Forevers: Life, Death, and Hope in a Mumbai Undercity, by Katherine Boo

A first-hand account of three years in a slum neighborhood in one of the biggest cities in the world, focusing on the hopes and challenges of two local families.

Infinite Vision: How Aravind Became the World’s Greatest Business Case for Compassion, by Pavithra Mehta and Suchitra Shenoy

A beautifully-written account of the history of a nonprofit South Indian eye hospital that has pioneered a revolutionary approach to eye-care which has brought relief to millions of poor people worldwide.

Steve Jobs, by Walter Isaacson

An unvarnished biography of the design and marketing genius who built  Apple and gained a place in business history alongside Thomas Edison, Henry Ford, and Sam Walton.

Top Secret America: The Rise of the New American Security State, by Dana Priest and William M. Arkin

The troubling story of the institutionalization of a new military-intelligence complex triggered by 9/11 and accelerated by the wars in Iraq and Afghanistan.

In the Garden of Beasts: Love, Terror, and an American Family in Hitler’s Berlin, by Erik Larson

The long-overlooked story of FDR’s ambassador to Nazi Germany and his frustrated efforts to turn U.S. policy against Hitler in the face of horrific violence against Jews in Germany and anti-Semitism in the State Department.

The Emperor of All Maladies: A History of Cancer, by Siddhartha Mukherjee

An oncologist’s critical study of the diseases lumped together under the label of cancer and of humanity’s halting efforts to arrest and cure them.

Cleopatra: A Life, by Stacy Schiff

A fresh new take on one of history’s most powerful and fascinating women, long caricatured in popular fiction and history books alike.

The Devil’s Casino: Friendship, Betrayal, and the High Stakes Games Played Inside Lehman Brothers, by Vicky Ward

An illuminating tale of the people who set off the Great Recession, bringing to light the greed, self-delusion, and miscalculation that came so close to collapsing the world economy in 2008.

Cyber War: The Next Threat to National Security and What to Do About It, by Richard. A. Clarke and Robert K. Knake

A profoundly troubling look at the rapid rise of cyber warfare and the existential threat it poses to American civilization, written by the top counterterrorism official in both the Clinton and Bush Administrations.

The Immortal Life of Henrietta Lacks, by Rebecca Skloot

Based on ten years of dogged research, a science journalist’s deeply moving account of the African-American woman whose cancerous cells seeded six decades of medical discoveries.

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The Immortal Life of Henrietta Lacks, by Rebecca Skloot

A review of The Immortal Life of Henrietta Lacks, by Rebecca Skloot

@@@@@ (5 out of 5)

The Immortal Life of Henrietta Lacks is extraordinary on several levels: as a beautifully researched work of medical and scientific history, as a portrait of the profound impact of racism in America, and as a brutally honest first-person account of a writer’s challenging, decade-long struggle to write a serious book. If The Immortal Life of Henrietta Lacks doesn’t win at least one of the major awards for books published this year, I’ll be hugely disappointed.

The text on the cover telegraphs the essence of the story: “Doctors took her cells without asking. Those cells never died. They launched a medical revolution and a multimillion-dollar industry. More than twenty years later, her children found out. Their lives would never be the same.”

Henrietta Lacks, we discover, was an ill-educated African-American woman who died of cervical cancer at the age of 31 nearly sixty years ago. She was a patient at Johns Hopkins Hospital in Baltimore, home of one of the nation’s most prestigious medical schools and of some of the world’s leading researchers in fields such as cell culture and oncology. One of those researchers asked Henrietta’s physician for a sample of her diseased cervix in faint hopes that, unlike every other tissue sample anyone to that date had ever tested, the cells he extracted would divide indefinitely,thus become “immortal,” and open up new vistas for medical research. To his and everyone else’s astonishment, they did. And not only did those cells continuously divide from 1951 to the present, they proved to be so aggressive and so persistent that they contaminated every other cell culture they came in contact with — invalidating years of medical research that was conducted before the contamination was discovered. To this day, HeLa cells, named as a contraction of Henrietta’s name, constitute one of medicine’s most pervasive experimental tools.

The medical history in this book is engrossing. As Skloot amply demonstrates, it’s also scientifically significant. But for me what was most powerful about The Immortal Life of Henrietta Lacks was the unfolding story of Henrietta’s life and of the lives of her many children and grandchildren. Skloot devoted a decade to befriending and later interviewing Henrietta’s daughter, Deborah, Deborah’s brothers, and other influential members of the Lacks family in Virginia and Maryland. Theirs is one of the most dramatic and moving tales I’ve ever encountered of the profound impact of racism in our society. At Deborah Lacks’ insistence, Skloot reported every incident and every conversation precisely as it occurred, with no sugar-coating. The power of her reporting is irresistible.

Rebecca Skloot is an accomplished science journalist, but amazingly this is her first book. If she never writes another one, her contribution to the history of medicine and science will be assured.

ISBN-10: 1400052173

ISBN-13: 978-1400052172

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